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The resulting increase in GABA release helps restore the balance of excitatory and inhibitory neurotransmission by decreasing glutamate activity, promoting neuronal survival, and enhancing mitochondrial function

Do not take two doses close together unless your clinician tells you to

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They are often prescribed if: Metformin is not effective or tolerated Your A1C is still high despite other medications You are at risk for heart failure, kidney disease, or atherosclerosis These medications are used with diet, exercise, and other diabetes treatments