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The higher number of X-junctions in correlation with T-junctions, the more integrated the town centre is on a local as well as global scale
The nausea and appetite suppression it causes follow directly from the locations of those receptors (Wilding et al., NEJM 2021)
Still, this recommendation should be carefully generalized to other medicinal products, especially when treating patients with background gastroparesis or kidney dysfunction, or when considering drugs with narrow therapeutic effects
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