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Hair loss from GLP-1 is temporary telogen effluvium caused by rapid weight loss and metabolic stress, not medication toxicity

Depending on cellular state and stress cues, TP53 can promote ferroptosis by repressing SLC7A11 to limit cystine uptake and GSH synthesis, inducing spermidine/spermine N1-acetyltransferase 1 ( SAT1 ) to enhance ROS generation through polyamine catabolism, and upregulating glutaminase 2 ( GLS2 ) to increase -ketoglutarate production and mitochondrial ROS 154-156

Why do we need JAK inhibitors in systemic lupus erythematosus