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M2 macrophages exhibit angiogenic and proinvasive properties, producing growth factors, chemokines, and MMPs that stimulate tumor growth, invasion, and metastasis (93), particularly facilitating tumor cell extravasation and growth in secondary sites

Cappariloside A suppresses the inflammatory response induced by mouse lung-adapted influenza virus strains

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Topiramate affords neuroprotection in diabetic neuropathy model via downregulating spinal GFAP/inflammatory burden and improving neurofilament production

By directly interacting with specific GH receptors expressed across multiple tissue types, investigators can comprehensively study systemic hormonal effects