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36 Moreover, GLP-1 RAs improve lipid profiles by decreasing serum cholesterol and triglyceride levels and increasing high-density lipoprotein (HDL) levels contributing to cardiovascular protection

It can contribute to tumor growth by promoting the death of immune cells that would otherwise impede cancer progression

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However, the Eli Lilly lawsuit filed in April 2025 alleges marketing practices similar to those cited in the FDA warning letters: referencing branded drug clinical trials and selling tirzepatide in unapproved oral formats

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