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Start your intake When Does Semaglutide Start Working After First Injection Semaglutide reaches peak blood levels approximately 1 to 3 days after injection, though some people report appetite reduction as soon as 12 to 24 hours

Nausea appears within the first 24 to 72 hours

Skin elasticity using a cutometer was measured at baseline, at 4 weeks, and then 4 weeks after discontinuation of the treatment, which showed significant improvement in skin elasticity, even in sun-exposed skin areas, during these time points compared with baseline values [39]

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