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Insulin aspart, like human insulin, caused pre- and post-implantation losses and visceral/skeletal abnormalities in rats at a dose of 200 units/kg/day (approximately 32 times the human subcutaneous dose of 1 unit/kg/day, based on human exposure equivalents) and in rabbits at a dose of 10 units/kg/day (approximately three times the human subcutaneous dose of 1 unit/kg/day, based on human exposure equivalents)

The therapy demonstrated significant anti-fibrotic efficacy: at week 96, 49% of patients in the high-dose group achieved at least a one-stage fibrosis improvement without worsening of MASH

Out of the three primer type products, this one may be the most expensive but hypothetically should work better for different skin types

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