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Research published in obesity journals confirms that hormonal and neurological changes make weight maintenance significantly harder after stopping GLP-1 therapy without structured support

FDA has also warned companies that have illegally sold unapproved drugs containing semaglutide, tirzepatide or retatrutide that are falsely labeled for research purposes or not for human consumption . These products have been sold directly to consumers for human use with dosing instructions

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Eli Lilly makes both the dual-agonist and triple-agonist drugs