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Part of the reason for the weight loss drug boom is simple: an increase in the number of overweight and obese people, widely dubbed the obesity epidemic. The epidemics existence, however, is deeply intertwined with the diet industry

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Our results are consistent with previously reported changes in targeted-metabolite levels (butyrates, carnitines, BCAAs, citrate, uridine, and urate) 2,16,20,27 , which in turn, validate the protocol used here

This review article is based on previously conducted studies and does not contain studies with human participants or animals performed by any of the authors