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A 12-week randomized trial demonstrated: Average weight loss of 2.6 kg in AOD-9604 group (1 mg/day) versus 0.8 kg in placebo group Preferential reduction in abdominal and visceral fat deposits No adverse effects on carbohydrate metabolism or insulin sensitivity Non-dose-dependent effects, with higher doses (10 mg/day) producing less weight loss than lower doses However, a subsequent 24-week Phase III trial with 502 subjects incorporating intensive diet and exercise showed no statistically significant weight loss compared to placebo, leading to development termination in 2007

AOD 9604 (3 mg) is a synthetic research peptide studied in models of weight regulation and metabolic function

5-AMINO-1MQ is a laboratory reference material supplied for qualified research and analytical applications only

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[1] Cardiovascular symptoms warrant urgent evaluation