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Sonnenburg JL, Bckhed F
17/768110 entitled Diagnosis and Treatment of Autism Spectrum Disorders Using Altered Ratios of Metabolic Concentrations and worldwide patent filings related to this work
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The drug therefore non-covalently associates with endogenous albumin upon administration, which extends the plasma half-life of the peptide from a few hours to 7 days, enabling once-weekly injections 93,94
The most common ones are usually mild and improve over time: Nausea (especially when starting) Diarrhea or constipation Decreased appetite Fatigue during adjustment period Stomach discomfort Serious But Rare Side Effects More serious side effects are uncommon but require medical attention: Severe allergic reactions Pancreatitis (inflammation of the pancreas) Gallbladder problems Low blood sugar (if combined with diabetes medications) Kidney problems Sleep-Related Considerations Some people report temporary sleep changes when starting GLP-1 medications: Initial insomnia or restlessness (usually improves) Changes in dream patterns Temporary fatigue as body adjusts Mood changes that can affect sleep Most sleep-related side effects resolve within a few weeks as your body adapts to the medication
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