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Detection of lipid peroxidation Peroxidation was examined by monitoring change in fluorescence emission of C11- BODIPY 581/591 from red to green 75

In each of these studies, treatment with RYALTRIS resulted in a statistically significant greater decrease from baseline in the overall RQLQ(S) than placebo (LS mean difference from placebo for Study 1: -0.5 [-0.8, -0.3]

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These IGF-I actions, taken together with its neuroprotective effects following CNS and peripheral nerve injury, suggest that it may be of therapeutic benefit in a wide variety of disorders affecting the nervous system