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Its Phase 2 weight loss data (24.2% at 48 weeks) and mechanistic advantages in hepatic fat reduction through glucagon receptor activation suggest it could surpass semaglutide's efficacy if Phase 3 results confirm the Phase 2 findings

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The most meaningful question is not just how much weight someone loses but what happens inside their body during and after that weight loss

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Five years ago, the Grammy-nominated artist weighed over 520 pounds, adding that it was the maximum number the scale he used could reach, he told Men's Health