8.4 Clinical differentiation in a post-GLP-1 landscape The success of incretin-based therapies has raised expectations for efficacy in metabolic disease, particularly in obesity, where benchmarks for weight loss and cardiometabolic improvement are now well established (Kushner and Kahan, 2024)
Recombinant Sec TGR Expression and Purification A bacterial-type SECIS element was fused to the TGR open reading frame [14] using PCR with the following oligonucleotides primers: forward 5-catATGCCTCCAGCTGATGGAAC-3 and reverse 5-TCGCCAACGACTCCAATTATTAGCCAACGTCCAGACGTGGTTAGCAATTGGATACGCGGGcagctg-3
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