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doi: 10.1038/s41419-020-03362-4

In conclusion, future research needs to intensify efforts on studying the complex interplay between oncometabolites, epigenetic changes, and CSCs

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Nature (2011) 474:5115

Review supplementation If elevated B12 results from excessive supplementation: Discontinue or reduce high-dose supplements unless medically indicated For patients receiving therapeutic B12 injections for confirmed deficiency, continue treatment as prescribedelevated levels are expected after replacement therapy and do not indicate toxicity Review with GP to ensure supplementation remains appropriate 3