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GPX4 is lowly expressed in gastric cancer (GC) cells, making them more susceptible to ferroptosis than normal intestinal cells

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2021 Dec 27;11(1):50

GLP-1 agonists are most often used by people with type 2 diabetes to manage blood sugar levels, but in recent years, theyve become a top treatment choice for people with overweight or obesity for weight management

While they found better skin outcomes in participants who used hydroquinone cream (a common melasma intervention), they also concluded that topical silymarin was also effective and produced fewer side effects.28 Wrinkles A lack of skin moisture is one of the factors behind fine lines and wrinkles.29 According to a 2012 study published in the African Journal of Biotechnology , milk thistle extract, emulsified into a topical cream, may help combat wrinkle formation by boosting moisture retention and preventing transepidermal water loss.30 An important caveat to consider is that all of our top recommended milk thistles are oral supplements, and research on oral milk thistle for the above purposes is somewhat lacking