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While Im excited about the future of these drugs development, the side effect profile isnt worth the risk for otherwise healthy patients

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Recent studies indicate phenolic compounds induce ferroptosis in multiple cell types by forming iron complexes that potentiate Fenton reactivity, leading to hydroxyl radical overaccumulation and ferroptosis-like death (Sui et al., 2024)

Physicians specifically screen for pancreatitis history, personal or family history of medullary thyroid cancer, and multiple endocrine neoplasia type 2, as semaglutide carries contraindications in these populations

None of them was taking medications known to cause hypoglycaemia, such as insulin or sulphonylureas