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found significantly increased plasma concentrations of anti-spectrin NAbs in splenectomized patients with -thalassemia major and in patients with sickle cell anemia (Wiener et al., 1986)

We dont have any idea of potency and efficacy of these drugs, Johnson said

Obviously, I asked for an meningitis B vaccine, but demonstrated to me the level of confusion that it caused, even for very seasoned pediatricians, who have been taking care of children for decades, that going away from a routine recommendation to more SCDM, without really providing both the health care professionals and the patients the tools, the information and ability to communicate with one another effectively really undermine the uptake of the vaccine

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