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Human brain organoids-on-chip: advances, challenges, and perspectives for preclinical applications

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In investigating the role of miR-1 in cardiac and skeletal muscle, it was shown that miR-1 expression level was decreased in cardiac hypertrophy mouse, while IGF-1 protein level was significantly increased, as compared to control (Sayed et al., 2007

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We observed only the full length SnCE1 being lysine acetylated whereas the autoproteolytically processed SnCE1 is not acetylated, which supports the conclusion that SnCE1 deacetylation is a prerequisite for proteolytic processing of SnCE1 (Fig