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Clinical trials have shown that rapidly improving blood sugar levels can worsen the existing eye damage in some patients

In this population, methylated B vitamins (methylcobalamin, methylfolate) bypass the impaired MTHFR enzyme and directly support SAMe production

Mechanistically, B12 deficiency leads to elevated homocysteine levels and impaired methylation pathways, contributing to neuronal toxicity and cerebrovascular damage

This research was funded in part by a National Institutes of Health General Medicine Grant (GM85024 to E.H.), a Forschungsstipendium of the Max Planck Society (to E.H.), a BBSRC CBMNet Proof-of-Concept Award (to E.H.), a National Institutes of Health Infectious Disease and Immunology Training Grant (to D.M.Z.), and a National Science Foundation Grant (1949762 to D.M.Z.)

Flavorless hard capsules eliminate unpleasant tastes, making it easier to incorporate into your daily routine