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Some of the blood tests include: Complete Blood Count (CBC) which usually indicates hemolytic anemia with increased WBCs (white blood cell counts) and microcytic anemia in children with a big spleen lower numbers of platelet count may be seen High-performance liquid chromatography (HPLC) and capillary zone electrophoresis (CE) system can distinguish Thalassemia Major and the carriers

But if you read the research, you will see that methyl B12 is best absorbed when dissolved in saline

doi:10.3390/ijms25031517