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60, 61 CTP1C expression displays an inverse correlation with the activation of mTOR pathway and attenuates tumor sensitivity to rapamycin (a mTOR inhibitor), 18 which suggests that the CPTIC-involved pathway parallels to mTOR-enhanced glycolysis

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Investigation of the pathways related to intrinsic miltefosine tolerance in Leishmania (Viannia) braziliensis clinical isolates reveals differences in drug uptake

Metalloproteinases can digest collagen and elastin, weakening the skin and causing sag

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