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Operational Impacts Care Management Programs: Plans must scale care management programs to handle up to 30% more members receiving GLP-1 prescriptions, requiring investment in digital tools and personnel
PubMed, Pham, Hung, et al
Retatrutide-related diarrhea followed a similar pattern to what researchers observe with tirzepatide GI side effects , typically resolving within the first few weeks of a given dose level
Mechanism of action: Activates GLP-1 receptors in the brain, gut, and pancreas Reduces appetite and food cravings Slows gastric emptying you feel full longer Stimulates insulin release, suppresses glucagon Improves blood sugar regulation FDA-approved brand names: Wegovy 2.4mg weekly, approved for chronic weight management Ozempic approved for type 2 diabetes
But he said he is also concerned about the fact that, for compounders, its challenging to get the right ingredients. And, as a result, human beings are injecting themselves with versions of GLP-1 drugs meant for laboratory studies, which, Aggarwal said, could be harmful. At the end of the day, these are real humans we are taking care of, he said
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