Side effects Overconsumption can cause gastrointestinal distress, nausea, bloating, and increased insulin levels
Zepbound (tirzepatide) studies generally show marginally better average weight loss outcomes compared to semaglutide at equivalent doses but Wegovy is highly effective, extensively studied, and costs the same copay on plans where it's preferred
Molecular dynamic investigations proposed that, in the process of ferroptosis, alterations in lipid composition cause changes in cellular membrane shape and curvature, leading to exposure to more oxidants, irreversible destruction to the membrane integrity, and ferroptotic cell death (Jaganjac et al., 2020)
Phase 1 and 2 trials have recently been published, addressing its efficacy and safety for reducing body weight and improving the glycemic profile of patients with T2D and/or obesity
NAION causes devastating vision loss that occurs suddenly and usually affects one eye, though the second eye develops NAION in approximately 15-25% of cases within five years
