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Urolithin A prevents streptozotocin-induced diabetic cardiomyopathy in rats by activating SIRT1

Aliquots (~0.1 mg) of the target compounds were dissolved in methanolic KOH solution (1.2 mol/L, 80% MeOH), incubated at 50 C for 2 h, then adjusted to pH 5.0 and analyzed by means of UPLC-TOF MS in the negative electrospray mode

Effects of incretin-based therapy on other obesity-related comorbidities Incretin-based AOM might be beneficial for most of obesity-related comorbidities, notwithstanding their metabolic, load-bearing, and mixed pathogenesis (Fig

Its triple-agonist mechanism means it already covers three of the most important metabolic pathways in a single injection