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However, Defendants have downplayed the severity of the gastrointestinal events caused by their GLP-1RAs, never, for example, warning of the risk of gastroparesis (paralyzed stomach) and its sequalae. Mann presents claims of failure to warn and strict products liability, and seeks both compensatory and punitive damages

Dual agonists produce more weight loss on average in clinical trials, making them objectively more effective for total weight loss

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Figure 1: Obesity rates on the rise in the US Why

Monitoring : Regular HbA1c testing (typically every 36 months), weight monitoring, and renal function assessment