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In the analysis of SMR method, the results of the discovery cohort were similar to those of MR, while the results of the validation cohort were not statistically significant but still suggested a potential negative correlation between the two, and the results of the Meta-analysis still indicated that GLP-1R gene expression in blood tissues was significantly associated with a reduced risk of DR

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Tsujii S, Ishisaka M, Shimazawa M, Hashizume T, Hara H