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Patients with certain GLP1R variants may experience faster adaptation and shorter nausea windows, while others may need a slower dose escalation schedule

Disclaimer: Always consult a licensed healthcare provider to determine if a GLP-1 medication is appropriate for your health profile

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The clarified cell lysate was either directly submitted to further protein purification steps or flash-frozen in liquid nitrogen after addition of 10% glycerol and stored at 80 C for use in biocatalytic reactions