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investigated the therapeutic potential of polyphenolic extracts derived from Arabidopsis thaliana in an AD Drosophila model expressing A142

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The forty-eight experimental animals were randomly assigned to six groups ( n = 8 per group): a no treatment (NT) group, a GLP-1 (0.4 mg/Kg) group, a DSS (2%) group, and three DSS + GLP-1 (0.1, 0.2 and 0.4 mg/Kg) groups [2023]

Moreover, it is not possible to clarify whether these effects are fully secondary to weight reduction and if this drug class has other beneficial hepatocellular activities beyond weight loss