Available from: Accessed 09.11.2024 Blair JMA, Webber MA, Baylay AJ, Ogbolu DO, Piddock LJV
These effects are achieved by inhibiting the activation/phosphorylation of Src and STAT3 (which are related to sorafenib resistance) in hepatocellular carcinoma cells or tumors, reducing the nuclear levels of STAT3, and inducing the production of ROS [92]
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[6] Caution is advised in patients with advanced renal impairment or those receiving dialysis, given the renal clearance of carnitine and the risk of accumulation
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