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GHK peptide follicle regeneration GHK (glycyl-histidyl-lysine) is a copper-binding tripeptide that stimulates dermal papilla cell proliferation and protects them from apoptosis

Annexin V-staining and TUNEL analysis confirmed a synergistic induction of apoptosis

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Extracellular UDP-glucose activates P2Y14 receptor and induces signal transducer and activator of transcription 3 (STAT3) Tyr705 phosphorylation and binding to hyaluronan synthase 2 (HAS2) promoter, stimulating hyaluronan synthesis of keratinocytes

Ongoing studies continue to examine copper-mediated cellular signaling, extracellular matrix remodeling, tissue homeostasis, collagen biology, and cellular communication