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Meet our experts Gary Goldenberg , MD, assistant clinical professor of dermatology at the Icahn School of Medicine at Mount Sinai and dermatologist at Mount Sinai Hospital in New York City Cindy Wassef, MD, dermatologist at Premier Health Associates in Randolph, N.J

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Severe dehydration may cause confusion, a fast heartbeat, or inability to urinate and requires immediate medical care

This timing aligns with the medication's mechanism: semaglutide immediately begins slowing gastric transit, which your stomach interprets as an unfamiliar sensation before adaptation occurs

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