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Pre-Blend Reconstitution Math (12.5/2.5 mg, 15 mg total) Metric Blend composition Value 12.5 mg retatrutide + 2.5 mg cagrilintide Metric BAC water added Value 2.5 mL Metric Concentration Value 5.0 mg/mL retatrutide + 1.0 mg/mL cagrilintide Metric Ratio held constant Value 5:1 (reta : cag) What Each Draw Delivers (12.5/2.5 mg Pre-Blend) Draw Volume 0.20 mL Units 20 units Retatrutide 1.0 mg Cagrilintide 0.2 mg Draw Volume 0.40 mL Units 40 units Retatrutide 2.0 mg Cagrilintide 0.4 mg Draw Volume 0.60 mL Units 60 units Retatrutide 3.0 mg Cagrilintide 0.6 mg Draw Volume 0.80 mL Units 80 units Retatrutide 4.0 mg Cagrilintide 0.8 mg Draw Volume 1.20 mL Units 120 units* Retatrutide 6.0 mg Cagrilintide 1.2 mg Draw Volume 1.60 mL Units 160 units* Retatrutide 8.0 mg Cagrilintide 1.6 mg Draw Volume 2.40 mL Units 240 units* Retatrutide 12.0 mg Cagrilintide 2.4 mg * Volumes above 100 units exceed a standard 1 mL insulin syringe - split into two injections or use a larger syringe

Reference AOD-9604 Dosing Protocol In addition to its pill form, AOD-9604 is available for research as a lyophilized powder that should be reconstituted with bacteriostatic water and administered subcutaneously