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Interestingly, introduction and eventual acceptance of IDPs (which do not have unique structure and exist as highly dynamic conformational ensembles) played an important role in the subsequent SAXS developments reflected in the elaboration of approaches for characterization of protein mobility and flexibility by generating realistic ensemble models of unstructured states (Kikhney and Svergun, 2015)

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: Semax, an analog of ACTH(4-10) with cognitive effects, regulates BDNF and trkB expression in the rat hippocampus

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