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Tirzepatide (sold as Mounjaro and Zepbound) is FDA approved and available now, while Retatrutide remains in Phase 3 trials with expected approval sometime between 2026 and 2027

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So the drug is technically approved but legally blocked from sale domestically, at least for now

Raj Kannan, CEO of Alveus Therapeutics, which raised $160 million in series A financing in January, says the next generation of drugs is going to be all about the quality and durability of weight lossand that is where amylin analogs hold promise

Mazdutide (dual GLP-1/glucagon agonist): Both target glucagon, but retatrutide adds GIP receptor activation for a true triple mechanism