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An early example is the use of silver ions, which enable the cyclization of unprotected or minimally protected peptides

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doi:10.3233/JAD-142814 PubMed: 25649658 Sun X, Deng Y, Fu X, Wang S, Duan R, Zhang Y

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It has not been possible to determine which symptoms are due to carnitine deficiency and which are due to an underlying organic acidemia, as symptoms of both abnormalities may be expected to improve with levocarnitine