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While these effects can be uncomfortable, most are manageable with small lifestyle changes, hydration, and communication with your healthcare provider

GLP-1RAs, such as lixisenatide, not only rely on -cell function and glucagon suppression, but also assist to lower glucose by other (insulin-independent) mechanisms such as delayed gastric emptying, underlying the clinical utility of GLP-1RAs as adjuvant therapy to basal insulin in longstanding T2DM [14]

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Benzyl alcohol carries specific risks : Benzyl alcohol is contraindicated in neonates and should be used with caution in pregnancy and in individuals with known sensitivity

Efficacy and safety of lixisenatide once daily versus exenatide twice daily in type 2 diabetes inadequately controlled on metformin: a 24-week, randomized, open-label, active-controlled study (GetGoal-X)