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The overexpression of circ_0000250 in ADSC-EVs results in enhanced healing in diabetic mice through the induction of autophagy mediated by the miR-128-3p/SIRT1 axis since epidermal SIRT1 is responsible for the modulation of inflammation, wound healing and cell migration [120]

Each condition was performed in technical triplicate

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The first step is mediated by -glutamylcysteine synthetase (GCLC), which catalyzes the -amide bond between the -carboxyl group of glutamate and the amino group of cysteine to form -glutamyl-cysteine (-Glu-Cys)

Identification of thioredoxin-interacting protein 1 as a hypoxia-inducible factor 1alpha-induced gene in pancreatic cancer