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Key Model Systems and Endpoints for IGF-1 LR3 and MGF Research Primary human satellite cells (biopsy-derived, passage 13, Pax7+ sorted) are the gold standard in vitro system for both compounds

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In order to achieve the above object, the present invention adopts the following technical solutions: a synthetic method of Cagrilintide comprises the following steps: selecting 7-8 th amino acid of a Cagrilintide sequence as a pseudo-pro dipeptide Fmoc-Ala-Thr (pro-me-me) -OH, taking 10-11 th amino acid of the Cagrilintide sequence as a pseudo-pro dipeptide Fmoc-Ala-Thr (pro-me-me) -OH, and taking 21-22 th amino acid of the Cagrilintide sequence as a pseudo-pro dipeptide Fmoc-Ser-Ser (pro-me-me) -OH

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