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Among these, the Apolipoprotein E (APOE) gene, particularly the 4 allele (APOE4), stands out as the most significant and consistent genetic risk factor

doi: 10.3389/fcell.2026.1816014 Received 23 February 2026 Revised 16 March 2026 Accepted 24 March 2026 Published 21 April 2026 Volume 14 - 2026 Edited by Sabrina Gohlke, German Institute of Human Nutrition Potsdam-Rehbruecke (DIfE), Germany Reviewed by Atefeh Rabiee, The University of the Pacific, United States Christa Buechler, University Medical Center Regensburg, Germany Updates Copyright 2026 Soni and Abbott

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Mitochondria-lysosome contacts regulate mitochondrial fission via RAB7 GTP hydrolysis

doi: 10.1007/s00394-014-0822-9 62 McDermottM