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Imaging 47 , 20102015 (2020)
10.1016/j.biopha.2017.10.064 145 NguangS
it may resolve natural killer cell production Provide detox support: glutathione binds to toxins in the liver before they're excreted, so it may flush them out of your body Treat traumatic brain injury: glutathione may reduce oxidative stress, excitotoxicity, and inflammation while supporting mitochondrial function and aiding membrane, synapse, and axon repair Promote post-stroke healing: may protect cell function and perform reactive oxygen species scavenging in the brain Reduce fatty liver disease damage: may improve protein, enzyme, and bilirubin levels in alcoholic and nonalcoholic chronic fatty liver disease patients
In reaction to AD, astrocytes experience a shift in profile, one that is reactive and pro-inflammatory while losing homeostatic roles thus disrupting BBB integrity, ion and neurotransmitter buffering, and energy metabolism (Liddelow et al., 2017
These GST enzymes catalyze the binding of synthesized glutathione to electrophilic xenobiotics (foreign chemicals), reactive drug metabolites, and environmental toxins, effectively neutralizing their threat
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