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While not derived from botanical sources, its synthetically produced to match the naturally occurring compound in the human body

Schmidt EP, Yang Y, Janssen WJ, Gandjeva A, Perez MJ, Barthel L, Zemans RL, Bowman JC, Koyanagi DE, Yunt ZX, Smith LP, Cheng SS, Overdier KH, Thompson KR, Geraci MW, Douglas IS, Pearse DB, Tuder RM

At Advanced Medical Care in Queens and Brooklyn, our board-certified specialists see this connection often: poor sleep fuels oxidative stress, and oxidative stress, in turn, wrecks sleep

doi: 10.3389/fphar.2022.806470 [DOI] [PMC free article] [PubMed] [Google Scholar] 161

doi:10.1186/s12951-025-03248-7