In addition, treatment with 5-FU or AZ628 led to an increase in the intracellular levels of ferrous iron, as measured by confocal and flow cytometry of FeRhoNox-1 staining ( Figures 4E, F , and Supplementary Figures S3C, D )
Ramos Perez JM, Kadia TM, Montalban-Bravo G, Benton CB, Faderl S, Sasaki K, Naqvi K, Cortes JE, MD, Daver NG, DiNardo CD, Jabbour E, Borthakur GM, Al Azzawi H, Pemmaraju N, Konopleva MY, Pierce SA, Jain N, Ohanian M, Garcia-Manero G, Andreeff M , Kantarjian HM, Ravandi F, Alvarado Y
Know that there are several strategies to manage or reverse it
However, the body is generally very efficient at excreting excess B12 through urine without any issues
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