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What UK clinical guidance says The Wegovy Summary of Product Characteristics (the formal MHRA-approved prescribing document) section 4.6 states that semaglutide shouldnt be used during pregnancy, and that if a patient wishes to become pregnant, semaglutide should be stopped at least two months before a planned pregnancy due to the long half-life

Data sources also differ in whether they count: Current users or anyone who has ever used a GLP-1 Injectable GLP-1s only or both injectable and oral versions People with diagnosed diabetes or the general adult population Due to that, there is no single perfect number

Research efforts continue to explore various bicyclic topologies, aiming to establish novel synthetic pathways

PMID: 23900241

Kealy, R