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The results were presented by Novo Nordisk at the 58 th European Association for the Study of Diabetes (EASD) Annual Meeting 2022

Oral administration floods the gut lumen and intestinal lining with peptide, concentrating action locally

Potential side effects of L-carnitine supplementation include: Nausea Vomiting Stomach cramps Diarrhea A fishy body odor Muscle weakness in people with chronic kidney disease An increased risk of seizures in people with a seizure disorder Additionally, Tallent says L-carnitine supplementation may also elevate trimethylamine-N-oxide (TMAO) blood levelsa risk factor for atherosclerosis, the medical term for clogged arteries

Some patients restart treatment because they notice gradual changes in body composition after stopping, while others continue to maintain their results through nutrition, exercise, and healthy lifestyle habits without resuming therapy

Discontinuation rates due to adverse events were 12.2% at the 9 mg dose and 18.2% at the 12 mg dose in TRIUMPH-4