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Surely the model mimics the organ injury observed in patients with iron intoxication

Furthermore, in our effort to shed light on the molecular mechanism underlying ATZs ability to lower serum levels of testosterone, FSH, and LH, we examined the expression of certain genes and discovered that exposure to ATZ significantly downregulated the relative expression levels of 3-HSD , StAR , and CYP11A1 , which may help to explain why exposure to ATZ lowers these hormone levels

[6] Blood tests may show fewer but larger red blood cells, low numbers of young red blood cells, low levels of vitamin B 12 , and antibodies to intrinsic factor

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