Long-acting agents (e.g., semaglutide weekly, dulaglutide weekly) provide sustained receptor activation, improving both fasting and postprandial glucose
Huang, 2006)
Carvajal-Z O, Barradas-D DM, Hayward-Jo PM, Aguilar-Us MG, Nolasco-Hi C, Quero-Herr S, et al
Future trials or post-marketing data will need to establish whether retatrutide allows dose reduction for maintenance without significant weight regain
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