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That suggests it could be useful as a complementary therapy when these other medications are prescribed

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Finally, while rodent models demonstrate compelling proof-of-concept (e.g., SCFA supplementation ameliorates OA), the translatability of these findings to human physiology, with its greater complexity and longer disease course, is a significant hurdle that future research must overcome (30)

The mean changes in height SDS from baseline in years 2 through 5 of treatment were + 0.9 (SD = 0.8), + 0.8 (SD = 0.9), + 1.1 (SD = 1.0), and + 1.1 (SD = 1.1), respectively