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The steepest weight loss phase occurs between weeks 12 and 24

To increase IGF-I levels for promoting increased muscle growth and regenerative capacity, the most straightforward approach is to deliver IGF-I systemically

Your BMI Puts You in the Treatment Range The FDA-approved criteria for prescription weight loss medication are straightforward: BMI of 30 or higher (classified as obesity), or BMI of 27 or higher with at least one weight-related condition such as type 2 diabetes, high blood pressure, sleep apnea, or high cholesterol If your BMI is in this range, you meet the basic clinical threshold

Observational studies and some ophthalmology commentaries have been more reassuring overall, suggesting that many patients taking semaglutide do not experience clinically meaningful retinal worsening