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Forkhead transcription factor FOXO subfamily is essential for reactive oxygen species-induced apoptosis

In experimental settings using AGS cells infected with H

Mortazavi S, Vadoud S, Moghimi H

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The immunofluorescence co-staining experiments on colonic tissue sections showed that, in the DSS groups, the fluorescence intensities of GPX4 (ferroptosis marker, red) within EpCAM-positive epithelial cells (intestinal epithelial cell marker, green) were significantly reduced, indicating that intestinal epithelial cells underwent ferroptosis